The influnce of some nematodes infection on some hematological and sreum biochemical parameters in clarias gariepinus at dakahlia governorate

Abstract EN

The Clarias gariepinus fishes were naturally infected with nematodes and these affect on their biological activities and loss of weight and production of fishes.

This study was conducted on 100 fishes of Clarias gariepinus that collected from River Nile and their tributaries in Dak-ahlia governorate.

These fishes were subjected to clinical, postmortem, and parasitological examination to investigate the prevalence of the diseases caused by nematodes of Procamallanus Laeviconchus and Paracamallanus Cyathopharynx were 20% of infestation (Mahfouz 1991).

The clinical examination of infested fishes showed the presence of inflammation, adhesions in stomach, intestine, liver and kidney.

Infested fishes were emaciated and anemic.

The histophathological changes showed thickended with odema and hyperemia in intestinal mucosa.

In liver present fibrosis in bile ductules and degenerative and degeneration in hepatic cells.

The renal epithelium showed coagulative necrosis and haemorrhages and thickned renal capsule in kidney.

Effect of nematodes on Clarias gariepinus was evaluated through holding blood haemogram : Total erthrocytic count, total leukocytic count, haemoglobin concentration, packed cell volume and serum analysis for biochemical parameters including levels of glucose, total protein, albumin, total globulin and liver and kidney functions.

The total RBCs count, Hb concentration and PCV value were significantly decreased.

The total leucocytic count registered very highly significant increase resulting in raising cellular immune response.

The glucose level and A / G ratio were observed to be significantly decreased, also total protein and total globulin were highly significantly decreased, in addition to albumin level was very highly significantly decreased.

Serum AST and S.

ALT showed very high significant increase, serum creatinine and blood urea levels increased significantly.

A treatment trial was done by using bendazol as prolonged immersion bath treat-ment in dose 2mg / L for 3 weeks.

Fish were completely treated, where the blood analysis revealed that all parameters returned nearly to their normal values.