Therapeutic value of low energy laser with and without photosensitisation in wounds infected with staphylococcus aureus

Abstract EN

Background : the worldwide rise in antibiotic resistance has increasing negative influence on wound healing.

This has necessitated the development of novel antimicrobial and healing aid strategies.

Low energy laser therapy (LELT) has been shown to be one of the promising new methods in this aspect.

Objective : to evaluate the effect of LELT with and without a photosensitizer on infected wounds in guinea pigs.

Methodology : A triangular wound in the dorsal aspect of 60 guinea pigs was made and infected with staph.

aurous.

They were randomly divided into 4 groups after 24 hours.

Group I was treated daily with LELT (dose : 43.2j / cm2) and toluidine blue O (TBO) as a photosensitizer at a concentration of 12.5 µg / ml.

Group II received LELT only at the same dose as in group I.

Group III was treated conventionally with Beta dine-soaked sterile gauze daily.

Group IV had no treatment to act as a control.

Results : LELT with TBO produced significantly the best results compared to the other 3 groups with regard to anti-bacterial activity, purulence reduction and wound healing rate.

This effective, safe, painless and non-touch technique deserves to be considered in the management of wounds infected with staph.

Aurous.