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Effects of ovariectomy and thyroidectomy on course and outcome of trichinella spiralis infection in rat
Joint Authors
Ali, Nihad M.
Ahmad, Najla Samir
Thabit, Halah S.
Thabit, Sahar S.
Source
Journal of the Egyptian Society of Parasitology
Issue
Vol. 38, Issue 1 (30 Apr. 2008), pp.29-48, 20 p.
Publisher
The Egyptian Society of Parasitology
Publication Date
2008-04-30
Country of Publication
Egypt
No. of Pages
20
Main Subjects
Topics
Abstract EN
Physiological hormones modulate immune responses and implicate in associated susceptibilities to infections.
To clarify these endo-crinological effects, the influence of estrogen and thyroid deficiency, due to ovariectomy and thyroidectomy, respectively, on course and outcome of Trichinella spiralis infection in rats was studied.
While in ovariectomized rats there was significant increase in both adult and muscle larval counts as compared to intact infected rats, in thyroidec-tomized rats there was a significant increase in larval but not in adult count.
Combined ovariectomy and thyroidectomy resulted in signific-ant increase in both adult and larval counts.
Serum CPK and blood glucose were significantly elevated in ovariectomized and/or thyroid-ectomized rats as compared to intact infected one.
The deficiency of female sex hormones, and / or thyroid hormones in T.
spiralis infected rats affected the host resistance to infection by increasing parasite burden influencing the course and outcome of parasitic infection.
American Psychological Association (APA)
Thabit, Halah S.& Thabit, Sahar S.& Ali, Nihad M.& Ahmad, Najla Samir. 2008. Effects of ovariectomy and thyroidectomy on course and outcome of trichinella spiralis infection in rat. Journal of the Egyptian Society of Parasitology،Vol. 38, no. 1, pp.29-48.
https://search.emarefa.net/detail/BIM-280127
Modern Language Association (MLA)
Thabit, Halah S.…[et al.]. Effects of ovariectomy and thyroidectomy on course and outcome of trichinella spiralis infection in rat. Journal of the Egyptian Society of Parasitology Vol. 38, no. 1 (Apr. 2008), pp.29-48.
https://search.emarefa.net/detail/BIM-280127
American Medical Association (AMA)
Thabit, Halah S.& Thabit, Sahar S.& Ali, Nihad M.& Ahmad, Najla Samir. Effects of ovariectomy and thyroidectomy on course and outcome of trichinella spiralis infection in rat. Journal of the Egyptian Society of Parasitology. 2008. Vol. 38, no. 1, pp.29-48.
https://search.emarefa.net/detail/BIM-280127
Data Type
Journal Articles
Language
English
Notes
Includes appendices : p. 47-48
Record ID
BIM-280127