Preparation and characterization of Schiff base chelates derived from salicylaldehyde and tryptophane

Abstract EN

The new Schiff base chelates derived from Salicylaldehyde and Tryptophane with Mn (II), Co (II), Ni (II), Cu (II) ions have been prepared and characterized by using different techniques, such as elemental analysis , molar conductance measurements, thermogravimetric analysis, magnetic moment measurements, infrared and electronic spectra.

The elemental analysis data show the formation of 1 : 2 (M : L) ratio of the general formula of Na2 (ML2)nH20, where M and L are the metal ions and ligand under investigation, and n+1, 1.5, 2, 5.5 and 16.5.

The molar conductances of the prepared schiff base chelated indicate a non-electrolytic nature.

The thermogravimetric analysis data of Na2 (Mn (L) 2l6.5H20 reveal the presence of water molecules.

The magnetic moment measurements of the chelates exhibit a paramagnetic phenomenon except Cd (II) chelate is diamagnetic.

The infrared spectral data of the Schiff base and its chelates display the proper functional groups which take place in the complexation.

The electronic spectral data show the existence of n-n*, n- %* (HC = N) transitions.

The Schiff base and their chelates have been tested for their antibacterial activities against several human pathogenic bacteria (some of which were resistant to commercially used antibacterial).

The results showed a great activity of Cd (II) chelate against Escherichia coli, Salmonelle typhi, pseudomonas aeruginosa, and Staphylococcus aureus.

No effect of other compounds tested is observed against all bacteria used.

Therefore, the use of Cd (II) chelate can be recorded as an antibacterial agent after further investigation on it's toxicity.