Study antidiabetic effect of momordica charantia (bitter gourd)‎ seeds on alloxan induced diabetic rats

Abstract EN

The aim of the present study is to investigate the antidiabetic effect of the aqueous extract of Momordica charantia seeds in alloxan-induced diabetic rats.

Forty male albino Wistar rats were used, divided randomly into four groups (10 each).

Oral administration of the seed extract at a dose of 150 mg/kg B.W.

for 30 days showed a significant decrease in fasting blood glucose.

Our results were greatly lower after oral administration of aqueous extract of Momordica charantia seeds in alloxan-induced diabetic groups than glibenclamide treated group.

Also Momordica charantia extract and glibenclamide administered rats showed progressive increase in body weight.