Antibacterial activity of calendula officinalis flowers in vitro

Abstract EN

Flower samples of Calendula officinalis were collected from the gardens of the college of Pharmacy in Baghdad city to examine their antibacterial activity .The effect of ethanol crude extract of petals and reproductive parts of flowers in different concentrations were obtained and bioassayed in vitro for its bioactivity to inhibit the growth of eight types of bacteria .The extracts of petals part were clearly superior for all bacteria especially the bacteria Pseudomonas aeruginosa (inhibition zone was 25mm in the concentration 100 mg / ml) from gram negative bacteria, and Staphylococcus aureus (inhibition zone was 14 mm in the concentration 50 mg / ml) from gram positive bacteria, while the extracts of reproductive parts were less effective than petals part.

These results confirm the antibacterial activity of Calendula officinalis flowers and support the traditional use of the plant in the therapy of bacterial infection.