Study of type 1 fimbriae of escherichia coli in diabetic and non diabetic female patients with urinary tract infection

Abstract EN

Ninety nine isolates of Escherichia coli have been isolated and detected from un married female patients with UTI, (55) isolates were related to diabetic female and (44) isolates were related to non-diabetic female during the period between February and June 2008 in Hilla province.

The patients ages ranged from (11–30) years.

Haemagglutination assay (HA) has been used to detect the ability of E.

coli isolates to produce colonization factor (Type 1 fimbriae).

It has been found that 45 (81.8 % ) among (55) isolates from diabetic female with urinary tract infection have ability to produce Type 1 fimbriae, while 20 (45.5 % ) among (44) isolates of non-diabetic female with urinary tract infection have ability to produce this factor.

The effect of such antibiotics as (Ampicillin, Ciprofloxacin, Ceftazidime and Nitrofurantion) on colonization factor (Type 1 fimbriae) has also been studied and it has been found that these antibiotics causes complete inhibition to this factor.