The levels of protein oxidation and lipid peroxidation in sera of obese men

Abstract EN

Background : obesity is an important risk factor for the development of different type of degenerative diseases.

Objective : investigate the relationship between oxidative stress and obesity.

Methods : 30 Obese (BMI 34-42 kg / m2) subjects and 20 non-obese (BMI 23-24 kg/m2)subjects were subject to the present study.

Conjugated diene lipid hydroperoxides (CD), protein carbonyls, serum uric acid and total serum protein were determined spectrophotometric ally.

Results : results of present study show highly significant (P < 0.001) increase in the levels of CDH and total carbonyl group and show increase in total protein whereas shows decrease in uric acid levels of obese men, when compared with control group.

Conclusions : increase the levels of oxidation product and decrease the antioxidant levels indicate involvement of obesity in the conditions of oxidative stress.