The relationship between serum copper and the copper zinc ratio with malondialdehyde in patients with ovary cancer

Abstract EN

The study was designed to evaluate the relationship between serum copper and the copper / zinc (Cu / Zn) ratio with malondialdehyde (MDA) in patients with ovary cancer.

Blood samples were taken from Oncology Unit in Merjian Teaching hospital in Hilla city.

Thirty six patients suffer from ovary cancer were chosen in our study and thirty six healthy controls (group control).

We found that significantly increased lipid peroxidation, measured as MDA, was demonstrated in the serum of ovary cancer patients (p > 0.02).

The mean serum copper level in patients with ovary cancer was significantly higher than the control group (p > 0.01).

In addition, the mean serum zinc level in patients with ovary cancer was significantly lower than the control group (p > 0.04).

Moreover, a positive correlation was also observed between copper and the Cu / Zn ratio with MDA levels in the patient group but not in the control group.