Histological evaluation of intrabony defect repair induced by white ordinary portland cement (WOPC)‎

Abstract EN

Background : recently the ordinary Portland cement (OPC) has been analyzed and compared physically, chemically and biologically to mineral trioxide aggregate MTA and because of the similarity between OPC and MTA, So the Possibility of using Portland cement as a less expensive alternative to MTA in dental practice should be considered.

In view of this, the Present study is to evaluate the biological response of the jaw bone to intraosseous ordinary Portland cement (OPC) implantation.

Materials and Methods : fifteen local breed adult male rabbits divided into three groups of five rabbits, each rabbit has receive two intrabony defects in the mandible bone, one filled with white ordinary Portland cement (WOPC), the other left empty as a control The histological sections obtained after 1, 4 and 8 weeks postoperatively.

The histomorphometric analysis including counting of bone cells (osteoblasts and osteoclasts) , inflammatory cell and observation of the degree of inflammation and the type of bone reaction to OPC material.

Results there was no significant difference in inflammatory response between OPC group and control group at all period of time, , there was significant increase of osteoblasts number at one and four weeks interval of OPC group when compare with the control groups but at eight week there were no significant difference of osteoblasts number between them, control group showed highly significant increase of osteoclasts number at four and eight weeks interval when compare to OPC groups.

Most of OPC group and in all period of time showed bone deposition in direct contact with ordinary Portland cement (Type I bone reaction).

Conclusions : As a result we can conclude that the OPC material show high degree of biocompatibility, induce bone healing and act as bioactive material.