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The study of oral manifestations, oxidative stress marker and antioxidants in serum and saliva of rheumatoid arthritis patients
Joint Authors
Hadi, Zahrah K.
Zaydan, Taghrid Fadil
Source
Journal of Baghdad College of Dentistry
Issue
Vol. 23, Issue 3 (30 Sep. 2011), pp.74-79, 6 p.
Publisher
University of Baghdad College of Dentistry
Publication Date
2011-09-30
Country of Publication
Iraq
No. of Pages
6
Main Subjects
Topics
Abstract EN
Background : Rheumatoid arthritis (RA) is a heterogeneous disease with a spectrum of clinical severity ranging from mild arthritis to a crippling joint disorder with internal organ involvement.
Besides the immunological reaction, there is another biological process, based on the injurious activity of free radicals, playing a major role in the pathogenesis ; an increase in the generation of oxidants and lipid peroxidation products was demonstrated in the serum of RA patients, which correlated with the antioxidant levels.
Subjects, Materials and Methods : Seventy six individuals were enrolled in this study ; Fifty one of them were patients having RA ; twenty five were healthy control individuals matching the patients in age and sex.
Serum and saliva samples have been taken from each subject for biochemical analysis.
Results : The highest number of RA patients was of mild disease activity, while the lowest number was of inactive disease activity.
Xerostomia was the most prominent oral manifestations of RA patients.
The mean of serum and saliva MDA and UA in RA patients was significantly higher than of the healthy controls.
The mean of serum and saliva caeruloplasmin in RA patients was higher than that of the healthy controls.
Conclusion : Rheumatoid arthritis patients were associated with increased oxidative stress, antioxidants and inflammatory markers..
Patients with RA have different oral manifestations xerostomia were the most prominent.
The highest number of RA patients was of mild disease activity.
American Psychological Association (APA)
Hadi, Zahrah K.& Zaydan, Taghrid Fadil. 2011. The study of oral manifestations, oxidative stress marker and antioxidants in serum and saliva of rheumatoid arthritis patients. Journal of Baghdad College of Dentistry،Vol. 23, no. 3, pp.74-79.
https://search.emarefa.net/detail/BIM-288011
Modern Language Association (MLA)
Hadi, Zahrah K.& Zaydan, Taghrid Fadil. The study of oral manifestations, oxidative stress marker and antioxidants in serum and saliva of rheumatoid arthritis patients. Journal of Baghdad College of Dentistry Vol. 23, no. 3 (2011), pp.74-79.
https://search.emarefa.net/detail/BIM-288011
American Medical Association (AMA)
Hadi, Zahrah K.& Zaydan, Taghrid Fadil. The study of oral manifestations, oxidative stress marker and antioxidants in serum and saliva of rheumatoid arthritis patients. Journal of Baghdad College of Dentistry. 2011. Vol. 23, no. 3, pp.74-79.
https://search.emarefa.net/detail/BIM-288011
Data Type
Journal Articles
Language
English
Notes
Includes appendices : p. 77-79
Record ID
BIM-288011