Salivary enzymes as markers of chronic periodontitis among smokers and non smokers

Abstract EN

Background : the periodontal cells contain many intra cellular enzymes like alanine aminotransferase (ALT).

asparate aminotransferase (AST), and lactate dehydrogenates (LDH) that are released outside into the saliva and gingival crivicular fluid (GCF) after destruction of periodontal tissue during periodontitis.

Aim of the study : To determine the activity of these enzymes in saliva among smoker and non smoker patients with chronic periodontitis, and its relation to the clinical periodontal parameters (plaque index PLI, gingival index GI, pocket depth PD and clinical attachment level CAL).

Material and methods : 40 samples of chronic periodontitis patients (20) non smokers and (20) smokers were collected for the study of salivary (AST), (ALT), and (LDH) levels were analyzed spectra metrically.

Result : statistical analysis revealed highly significant difference in LDH activity (142 ± 14.63IU / L) between smoker and non smoker groups with significant positive correlation between the activity of LDH and GI, PD and CAL among smokers.

Also significant positive correlation between AST, ALT, LDH enzymes and CAL in smokers.

Conclusion : The present study showed a significant positive correlation between CAL and all enzymes levels among smokers.