Toxic effect of lead on reproductive system in male albino mice

Abstract EN

This study conducted to determine the effect of lead (pb) on weight of somebody organs as well as male reproduction in albino mice, 20 albino Swiss mice (balb-c) used in this study, the animals were divided into four groups, treatment with lead at concentration (0, 0.1, 0.3 and 0.5) ppm for 7 days.

The results showed no significantly (P > 0.05) effect of treatment on body organs weight (liver, kidney and adrenal gland), except weight of spleen (P<0.05), while weight of testis, epidydmus, seminal vessels and prostate decreased significantly (P < 0.05) when compared with control especially at concentrations 0.3, 0.5 ppm, and the sperm parameter (grade activity, concentration of sperm in epidydmus and percentage of sperm abnormalities) showed significant effects (P < 0.05) in all treatment groups in comparsion with control group, and this effects may be due to of Pb accumulation in reproductive system and sperm parameter.