Hepatitis B,C and human immune deficiency virus among cancer patients attending the national center of public health laboratories, Aden

Abstract EN

In human being, significantly higher prevalence of communicable diseases, such as viral infections, are thoroughly studied and some of them were attributed to the development of some malignancies.

This study was conducted to report any association of some malignancies with hepatitis B and C and HIV viruses in patients attending the National Center of Public Health Laboratories in Aden.

Retrospectively, results of virology markers were collected during the period from January 2007 to August 2008.

A total of 449 patients with different malignancies, were investigated before the start of chemotherapy.

The common types of malignancies reported among the studied patients were breast cancer (30.5%), gastrointestinal malignancies (21.2%), and lymphomas (17.8%).

Serological studies showed that the percentage of positive HIV, HBsAg and HCV were 0.4%, 4.7% and 8.0%, respectively.

Most patients with positive HBsAg were having gastrointestinal malignancies, mainly Hepatoceeular carcinoma (HCC) and non-Hodgkins lymphoma (NHL).

Patients with positive HCV were having gastrointestinal malignancies (mainly HCC), and lymphomas (Hodgkin's and NHL).

Positive HIV serology was reported in two patients; both of them were having NHL.

This study concluded that malignancies associated with viral infections were HCC (with HBV and HCV infections) and NHL (with HIV, HBV, and HCV infections), and recommended the treatment of such viral infections to help in decreasing the incidence of these malignancies.