Different treatment modilities of RAU

Abstract EN

Background: Recurrent aphthous stomatitis is the most common recurring oral ulcerative condition in many parts of the world, characterized by painful oral ulcerations recurring with varying frequency.

The aim of Study : To : investigate the most effective treatment of RAS according different treatment modalities.

Patients and Methods : This prospective study was performed on 80 patients and seen in period from January 2008 to August 2008.

80 patients that had recurrent aphthous ulcers were classified in to four groups according to the treatment modalities: Group I: Contained 20 patients, they were given a mixture of teaspoonful of each of (alarmin, dexon, and malox) syrup as mouth rinse three times daily.

Group II : Contained 20 patients, they were given tetracycline capsule (250 mg) as suspension in one spoon water used as rinse and spit four times daily.

Group III : Contained 20 patients, they were given chlorhexidine mouth wash (0.02 %) three times daily and Triamcinolone acetonide (kenalog) 0.1-0.5 % in orabase four times daily.

Group IV (Placebo group) : contained 10 patients, they did not take any treatment, we just gave them water colored with industrial food color.

Results : in this study 80 patients were examined, 53 of them 66.25 % were females, 27 patients 33.75 % were males.

Post-treatment daily observation on [first, third and sixth day] we looked for pain relief, reduction in size of ulcers, and complete healing.

Whole groups were included in the post-treatment observation that were took the treatment in the first day of appearance of their ulcers.

In the first day of observation, the pain disappeared in patients of group I, the intensity of pain reduced in patients of groups II and III, but patients of placebo group their pain remained as it was.

In the third day of observation the patients of group I showed reduction of size and disappearance of erythema of their ulcers, while patients of other groups their pain reduced, but ulcers' sizes remained as it was.

In the sixth day of observation we noted that patients of group I had complete healing of their ulcers, patients of the groups II and III had reduction of ulcers' sizes.

Conclusions : from this study the researcher concludes that: The mixture of (alarmin, dexon, and malox) syrup seemed to be the most effective type of local medication in treatment of recurrent aphthous ulceration, patientsv that took that kind of treatment had short healing time and earlier pain relief than patients that took other types of treatments.