The effect of the poly vinyl pyrrolidone (PVP)‎ addition on biological properties of heat-cured acrylic resin denture base material

Abstract EN

Background : The most common materials used for fabrication of denture base are poly methyl methacrylate (PMMA) and methyl methacrylate (MMA).

Biocompatibility is especially relevant to prosthodontics and other restorative materials.

Materials and methods : Biocompatibility was evaluated in comparison with the control materials through subcutaneous implantation in the rabbits.

50 specimens were prepared, 5 specimens for each period interval of biological study.

Excision biopsies were taken after 1 day, 3 days, 7 days, 14 days, and 28 days.

Microscopically, the count of the inflammatory cells was used as a parameter in the evolution of the tissue response in relation to the tested material.

The biological properties of the prepared material were evaluated in comparison with the control denture base acrylic resin.

Specimens were grouped to two groups : Group 1 : poly (methyl methacrylate) + methyl methacrylate as control.

Group 2 : poly (methyl methacrylate) 80 %, poly vinyl pyrrolidone 20 % + methyl methacrylate as experimental.

Results : After 3, 7, 14 and 28 days there was no significant differences between means count values of experimental and positive control sections.

Conclusion : The biolcompatibity of poly vinyl pyrrolidone was similar to poly (methyl methacrylate).