Periodontal health status and biochemical study of gingival creviculer fluid among diabetics and non diabetic : comparative study

Abstract EN

Background: The aim of this study was to determine the relative influence of diabetes mellitus on periodontal parameters and to correlate between glucose content of gingival crevicular fluid and blood in diabetics and non diabetics.

Material and method: The sample composed of 105 participants.

Group I composed from 35 healthy subjects, group II composed from 35 patients were well controlled diabetics and 35 patients were moderately and poorly controlled diabetics.

The periodontal parameters which included Plaque Index (PL.I), Bleeding on probing (BOP) and gingival fluid flow (GFF) were recorded.

For sampling of gingival crevicular fluid (GCF), strips of filter papers were gently inserted into the selected crevice of 4 teeth, each filter strip was placed in distilled water, and the supernatant was used for assessment of glucose (GGF) and total protein (PGF).

Results: The mean for GGF was highest in group III (9.972±4.218) and the lowest was for group I (3.34±1.612).

For periodontal parameters the highest value was also for group III, were PL.I was 2.350±0.367 and mean GCF was 3.014±0.545.

There was weak correlation between periodontal and biochemical parameters.

Conclusion: Diabetic groups showed significant difference in periodontal parameters compared to control group.

Also significant increase in GGF and PGF compared to control group.

Key words: Diabetes mellitus, gingival crevicular fluid.

(J Bagh Coll Dentistry 2008; 20(1) 52- 57)