Determination of cefalexin by direct (UV- Vis)‎ spectrophotometer and indirect (flame atomic absorption)‎ technique

Abstract EN

A new method for the determination of the drug cefalexin in some Pharmaceuticals using (UVVis) and indirect Flame Atomic Absorption Spectrophotometer (FAAS), Fe III should forms a chelating complex with cefalexin (CEX–Fe III) at pH (1-8) and the best pH for the formation of (CEX-Fe III) chelating complex was (2).

The complex extracted with Methanol and Dimethy-Sulphoxide The mole-ratio method has been used to determine the structure of chelate (CEX -Fe III) and found to be 2 : 1 LM (Ligand : Metal).