Anti-fungal activity of punica granatum i.peels powder and extracts from pathogenic samples

Abstract EN

Thirty five samples were collected from patients (1-30) years old, suffered from, infected skin, rushes, boils, oral thrush, anal and vaginal itches.

Candida albicans 57.3 % (20 isolates) and Candida tropicalis 22.5 % (8 isolates) Aspergillus fumegatus 11.5 % (4 isolates) Aspergillus nigar 8.7 % (3 isolates), were isolated and identified from these samples.

Alcoholic andwater hot extracts of the punica granatum (Pomegranate) peels as well as the dried powder were prepared.

The anti-fungal activity of the extracts was evaluated by means of the agar-well diffusion assay.

The extract exhibited potent activity against yeast.

The Minimum inhibitory concentrations were 128-1024 μg / ml against Candida albicans and Candida tropicalis.

There was little difference between the activities of alcoholic extract and aqueous extract.

These results suggest the Pomegranate Peels extract which contains gallotanic acid as a promising anti-fungal Agent.