Effect of the aqueous extract of matricaria chamomilla on stress-ethanol induced acute gastric ulceration in rabbits
Joint Authors
Ahmad, Jawad H.
Ali, Nabil A.
Nimah, Nazirah Falih
Source
The Medical Journal of Basrah University
Issue
Vol. 24, Issue 1-2 (31 Dec. 2006), pp.66-69, 4 p.
Publisher
University of Basrah College of Medicine
Publication Date
2006-12-31
Country of Publication
Iraq
No. of Pages
4
Main Subjects
Topics
Abstract EN
The anti-ulcer effect of the aqueous extract of Matricaria chamomilla flowers (chamomile extract, CE) had been tested on stress-ethanol induced gastric ulceration in rabbits.
The first part of the study was to induce acute gastric ulceration by stress or stress–ethanol combinations.
Stress alone was unable to produce gastric ulcerations while ulcer was induced in the group of rabbits exposed to stress in the presence of ethanol (5ml / kg ) with a mean value of ulcer index of 108.3mm ± 29 (n = 8).
Histopathologically examination was done to confirm the effect of stress-ethanol combination on gastric mucosa.
The second part of the study was performed to investigate the pharmacological effect of various concentrations of the aqueous extract of chamomile (1 %, 4 % and 8 %) on gastric ulceration.
The extract was given 15 minutes before ethanol administration.
The results have shown a significant anti-ulcer effect of chamomile extract with mean values of ulcer index of 76.
4mm ± 14.2 (P < 0.01) ; 11mm ± 14.2 (P < 0.005) and 53mm±27.9 (P < 0.01) for the concentrations 1 %, 4 % and 8 % respectively as compared to the control value of 133.25 mm ± 46.2 (n = 8).
It is concluded that the extract of Matricaria chamomilla flowers has anti-ulcer effect.
American Psychological Association (APA)
Nimah, Nazirah Falih& Ali, Nabil A.& Ahmad, Jawad H.. 2006. Effect of the aqueous extract of matricaria chamomilla on stress-ethanol induced acute gastric ulceration in rabbits. The Medical Journal of Basrah University،Vol. 24, no. 1-2, pp.66-69.
https://search.emarefa.net/detail/BIM-290041
Modern Language Association (MLA)
Ali, Nabil A.…[et al.]. Effect of the aqueous extract of matricaria chamomilla on stress-ethanol induced acute gastric ulceration in rabbits. The Medical Journal of Basrah University Vol. 24, no. 1-2 (2006), pp.66-69.
https://search.emarefa.net/detail/BIM-290041
American Medical Association (AMA)
Nimah, Nazirah Falih& Ali, Nabil A.& Ahmad, Jawad H.. Effect of the aqueous extract of matricaria chamomilla on stress-ethanol induced acute gastric ulceration in rabbits. The Medical Journal of Basrah University. 2006. Vol. 24, no. 1-2, pp.66-69.
https://search.emarefa.net/detail/BIM-290041
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 69
Record ID
BIM-290041