Risk factors and labour outcome in parous women with pre-eclampsia

Abstract EN

This is a case-control study, carried out to estimate the frequency of parous women with pre-eclampsia among all deliveries conducted in the study period (September 2004 -September 2005) ; to identify demographic, medical and obstetrical risk factors that are associated with recurrence of pre-eclampsia in subsequent pregnancies as well as to assess perinatal outcome.

The study included 165 parous women with pre-eclampsia as (cases) compared to 200 normotensive parous women as (controls).

The study found that the incidence of parous women with pre-eclampsia was about 1 % of all deliveries.

Recurrence rate was about 55 %.

Advanced maternal age, body overweight and obesity, chronic hypertension, previous pre-eclampsia, long interval between pregnancies, previous preterm labor, poor antenatal care and family history of pre-eclampsia were the main risk factors associated with development of preeclampsia.

Higher rate of cesarean section for eclampsia, fetal distress and abruption placenta was found among parous women with pre-eclampsia as well as high rate of abruption placenta and postpartum haemorrhage as obstetrical complications.

Adverse perinatal outcome was reported in women with pre-eclampsia in term of high rate of preterm delivery, fetal death, low birth weight and low apgar scor.

In conclusion ; the overall recurrence of pre-eclampsia in subsequent pregnancies is still high with poor prognosis regarding maternal and perinatal morbidity and mortality.