Detection of Mycobacterial antigen and antibody in patients : with tuberculosis and their association with therapy
Joint Authors
Source
Iranian Red Crescent Medical Journal
Issue
Vol. 9, Issue 2 (30 Apr. 2007), pp.74-79, 6 p.
Publisher
Publication Date
2007-04-30
Country of Publication
United Arab Emirates
No. of Pages
6
Main Subjects
Topics
Abstract EN
Background: Little is known about changes in total antibodies occurring during the progression of tuberculosis or its treatment.
Using passive and reverse passive hemagglutination methods, mycobacterial antibody and antigen were determined in sera of patients with acute smear-positive pulmonary tuberculosis. Methods: Fifty-nine patients were studied in different groups according to the duration of treatment in various stages of disease.
The first group that did not undergo treatment showed a very low level of antibody.
The second group with less than 6 months of therapy had a mean antibody titer of about 1:70.
The third group underwent therapy for more than 6 months and their mean antibody titer was about 1:970.
The fourth group whose disease was under control and their treatments were discontinued, showed the highest level of antibodies (1:2760).
Results: A significant difference was found between the average antibody titers and the duration of treatment and course of disease.
No antigen was detected in any patients except in group 5. Conclusion: A high antibody response seemed to occur after treatment when the bacteria were disrupted and their antigens released.
Absence of antigen may be due to the formation of antigen-antibody complexes.
American Psychological Association (APA)
Hadi, N.& Kabirian, M.. 2007. Detection of Mycobacterial antigen and antibody in patients : with tuberculosis and their association with therapy. Iranian Red Crescent Medical Journal،Vol. 9, no. 2, pp.74-79.
https://search.emarefa.net/detail/BIM-29021
Modern Language Association (MLA)
Hadi, N.& Kabirian, M.. Detection of Mycobacterial antigen and antibody in patients : with tuberculosis and their association with therapy. Iranian Red Crescent Medical Journal Vol. 9, no. 2 (Apr. 2007), pp.74-79.
https://search.emarefa.net/detail/BIM-29021
American Medical Association (AMA)
Hadi, N.& Kabirian, M.. Detection of Mycobacterial antigen and antibody in patients : with tuberculosis and their association with therapy. Iranian Red Crescent Medical Journal. 2007. Vol. 9, no. 2, pp.74-79.
https://search.emarefa.net/detail/BIM-29021
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 78-79
Record ID
BIM-29021