Clinical effect of low level laser therapy on healing of recurrent aphthous ulcer and oral ulceration in Behcet’s

Abstract EN

Background: As the exact etiology of recurrent aphthous ulcer (RAU) remains unknown, therapeutic measures are challenging and difficult.

Low level laser therapy use in based on the concept that certain doses of specific wavelength can turn on or off certain cellular components or functions as well as aid in healing and reducing pain and swelling of oral lesions.

The aim of this study was to evaluate the clinical effect of low energy Gallium-Arsenide semiconductor diode laser, 904 nm, on the healing process of recurrent aphthous ulceration and oral ulceration in Behest's disease.

Patients and Methods : this study was performed on 47 patients, age range 12-58 years, with RAU lesions irradiated by laser into two doses (in alternative day), and divided into Control group: RAU patients without any treatment.

Group one: RAU in Behcet’s disease irradiated with 1.5 Joule laser.

Group two: RAU only, irradiated with 1.5 Joule laser.

The results obtained account for duration of lesions, size measurement, pain symptoms, and presence of erythema in three visits.

Results : it was shown that no difference in the healing process of RAU and oral ulcer in Behcet’s disease when compared with the control group after low level laser therapy, however when the lesion is less than 24 hours old, it was healed faster than control group.

In addition to that, pain symptoms disappear soon after laser therapy, or it regains in low intensity.

In RAU, healing process was reduced to a couple of days in initial stage of ulcer, however, a non-significant clinical difference was observed on healing process of RAU and oral ulceration in Behcet’s disease after LLLT in comparison with non-treated RAU lesions.

There was no statistical significant difference on healing process of RAU and oral ulceration in Behcet’s disease after LLLT.

Pain disappears soon after LLLT and this is temporary which recur in the next visit but in milder form.

Conclusion : dose and other parameters at which low level laser therapy (LLLT) is implemented influence effectiveness of the therapy.