Nonspecific colitis a forgotten entity in central Sudan

Abstract EN

Background : nonspecific colitis is an inflammatory Bowel Disease (IBD) that runs a clinically benign course.

Histopathologically it is characterized by superficial mucosal erosions with lymphocytic infiltration in the lamina propria with no granuloma. Aim of this study : is to describe the clinical presentation of Non-Specific Colitis (NSC), and to evaluate its response to 5-aminosalicylic acid (5-ASA) in Sudanese patients. Setting and Design: This study is a prospective cohort.

A total of 26 patients presenting with bloody, mucoid diarrhoea, lower abdominal pain or colonic mass were included in the study. Methods and Materials : A total of 26 patients presenting with bloody mucoid diarrhoea, lower abdominal pain with or without colonic mass were included in the study.

All patients underwent colonoscopy.

Statistical analysis: A descriptive statistical analysis was done using SPSS. Results : (19 %) of patients were males and 7 were females with male to female ratio of 3 : 1.

The majority of patients 16 (61.6 %) had bloody diarrhea while 18 (69.2 %) opened their bowel 4-6 times a day.

The majority 10 (38.8 %) had rectum and sigmoid involvement.

All patients showed a good response to 5-ASA. Conclusions : this study showed that NSC has clinical features that are very much similar to mild UC with a rather good clinical response to oral 5-ASA.