Assessment of nitrogen radicals and their scavenging activity in patients with end-stage renal failure
Joint Authors
al-Nimr, Marwan
Jalil, Nizam A.
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 23, Issue 2 (30 Apr. 2012), pp.290-295, 6 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2012-04-30
Country of Publication
Saudi Arabia
No. of Pages
6
Main Subjects
Topics
Abstract EN
Reactive oxygen species are implicated in cardiovascular disease in patients with chronic renal failure (CRF).
This study is aimed to assess the nitrogen radicals in patients with end stage renal failure (ESRF) referred for peritoneal dialysis.
A total of 36 patients with estimated cretonne clearance ≤ 15 mL / min were recruited from the Dialysis Unit at Al-Yarmouk Teaching Hospital in Baghdad, Iraq during 2009, and enrolled into the study.
The main causes of CRF were hypertension and diabetes mellitus.
The median levels of serum nitric oxide and peroxynitrite were 300 and 152 μmol, respectively.
Nitric oxide was not detected in the sera of 10 patients.
The sera of 12 patients showed ability to scavenge in vitro, the nitric oxide released by sodium nitroprusside.
Significant inverse correlation was found between serum peroxynitrite and either systolic (r = -0.402) or diastolic (r = −0.387) blood pressure.
Our study shows that production of nitrogen radicals is enhanced in ESRF and it is accompanied by limited activity of scavenging nitric oxide.
American Psychological Association (APA)
al-Nimr, Marwan& Jalil, Nizam A.. 2012. Assessment of nitrogen radicals and their scavenging activity in patients with end-stage renal failure. Saudi Journal of Kidney Diseases and Transplantation،Vol. 23, no. 2, pp.290-295.
https://search.emarefa.net/detail/BIM-292786
Modern Language Association (MLA)
al-Nimr, Marwan& Jalil, Nizam A.. Assessment of nitrogen radicals and their scavenging activity in patients with end-stage renal failure. Saudi Journal of Kidney Diseases and Transplantation Vol. 23, no. 2 (Apr. 2012), pp.290-295.
https://search.emarefa.net/detail/BIM-292786
American Medical Association (AMA)
al-Nimr, Marwan& Jalil, Nizam A.. Assessment of nitrogen radicals and their scavenging activity in patients with end-stage renal failure. Saudi Journal of Kidney Diseases and Transplantation. 2012. Vol. 23, no. 2, pp.290-295.
https://search.emarefa.net/detail/BIM-292786
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 294-295
Record ID
BIM-292786