Role of viruses in renal cell carcinoma
Joint Authors
Salehipoor, Mahdi
Behbahani, Abbas Behzad
Rahsaz, Murjan
Afrasiabi, Muhammad Amin
Gerami zadah, Bita
Khezri, Abd al-Aziz
Aghdaie, Mahdukht Husayn
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 23, Issue 1 (28 Feb. 2012), pp.53-57, 5 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2012-02-28
Country of Publication
Saudi Arabia
No. of Pages
5
Main Subjects
Topics
Abstract EN
To determine whether viral infections are related to renal cell carcinoma (RCC), we studied 49 patients with RCC (29 patients were males with age ranging from 30 to 81 years and a mean of 57.5 years ; 20 patients were females with age ranging from 36 to 70 years with a mean of 58.4 years) and 16 non-neoplastic kidney patients as controls.
Tissues specimens from study patients and controls were examined by nested polymerase chain reaction (PCR) to determine the presence of DNA of several viruses including human papilloma virus (HPV), Epstein–Barr virus (EBV), and polyoma viruses (BKV and JCV).
Our results revealed that 7 of 49 (14.29 %) RCC tissue specimens had HPV DNA compared with none of 16 non-cancer control subjects.
Regarding the HPV types, all the positive results were high-risk HPV types (type 16 in three and 18 in four patients).
The present study suggests that HPV infection, especially high-risk types, is associated with RCC.
However, more studies are necessary to demonstrate the molecular monogenic processes involved in this association.
American Psychological Association (APA)
Salehipoor, Mahdi& Khezri, Abd al-Aziz& Behbahani, Abbas Behzad& Gerami zadah, Bita& Rahsaz, Murjan& Aghdaie, Mahdukht Husayn…[et al.]. 2012. Role of viruses in renal cell carcinoma. Saudi Journal of Kidney Diseases and Transplantation،Vol. 23, no. 1, pp.53-57.
https://search.emarefa.net/detail/BIM-292880
Modern Language Association (MLA)
Salehipoor, Mahdi…[et al.]. Role of viruses in renal cell carcinoma. Saudi Journal of Kidney Diseases and Transplantation Vol. 23, no. 1 (Feb. 2012), pp.53-57.
https://search.emarefa.net/detail/BIM-292880
American Medical Association (AMA)
Salehipoor, Mahdi& Khezri, Abd al-Aziz& Behbahani, Abbas Behzad& Gerami zadah, Bita& Rahsaz, Murjan& Aghdaie, Mahdukht Husayn…[et al.]. Role of viruses in renal cell carcinoma. Saudi Journal of Kidney Diseases and Transplantation. 2012. Vol. 23, no. 1, pp.53-57.
https://search.emarefa.net/detail/BIM-292880
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 56-57
Record ID
BIM-292880