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Cytotoxicity and antimicrobial activity of salvia officinalis L. flowers
Other Title(s)
السمية الخلوية و التضاد الحيوي لنبتة الميرمية (salvia officianails L. flowers)
Joint Authors
Abd al-Majid, Muna A. M.
Husayn, Abu Bakr
Source
Sudan Journal of Medical Sciences
Issue
Vol. 3, Issue 2 (30 Jun. 2008), pp.127-133, 7 p.
Publisher
Omdurman Islamic University Faculty of Medicine
Publication Date
2008-06-30
Country of Publication
Sudan
No. of Pages
7
Main Subjects
Topics
Abstract AR
في هذه الدراسة تمت مقارنة السمية الخلوية و التضاد الحيوي للميثانول بتركيز 70 % المستخلص من زهور نبتة المرمية النامية في السودان مع المستخلص المائي.
حيث تمت معايرتها باستخدام معايرة الجمبري البحري السام.
وجد أن الميثانول المستخلص من نبتة المرمية يحتوي على جلوسيدات قلبية, فلافونيات, صابونيات و قلويات .
و لقد ثبت لهذه المشتقات تضاد حيوي للعنقوديات الذهبية و العديد من الجراثيم الأخرى مثل الزوائف و الكليبسيلا.
كما وجد له أيضا فعالية ذد الجمبري البحري تعادل 55–55.6 من lc 50 إذا لمشتق الميثانول بتركيز 70 % تضاد حيوي فاعل للجراثيم أكثر من المشتق المائي.
Abstract EN
In this study a comparison of the Cytotoxicity and antimicrobial action of the aqueous and 70% methanol extracts from the flower of the herbal species Salvia officinalis L.
(Lamiaceae), originating from Sudan was carried out.
Material and Methods : Aqueous, and aquatic methanolic extracts of S.
officinalis was investigated for its antimicrobial activity and cytotoxicity using brine shrimps lethality assay.
Results: The methanol extract was found to contain cardiac glycosides, flavonoids, saponins and alkaloids.
It exhibited antibacterial activities against Staphylococcus aureus, Bacillus stearothermophilus, Micrococcus luteus, Serratia mascences, Clostridium sporogenes, Escherichia coli, Klebsiella pneumoniae, Bacillus cereus, Pseudomonas fluorescence.
It was also found to be potent against brine shrimps with LC50 value of 55.1- 55.6 ppm.
The 70 % methanol extract has a stronger antimicrobial activity than the aqueous one.
Conclusion : This work has revealed further potentials of S.
officinalis L flowers as an antimicrobial agent, especially against P.
aeruginosa which is resistant to some antibiotics.
American Psychological Association (APA)
Abd al-Majid, Muna A. M.& Husayn, Abu Bakr. 2008. Cytotoxicity and antimicrobial activity of salvia officinalis L. flowers. Sudan Journal of Medical Sciences،Vol. 3, no. 2, pp.127-133.
https://search.emarefa.net/detail/BIM-293206
Modern Language Association (MLA)
Abd al-Majid, Muna A. M.& Husayn, Abu Bakr. Cytotoxicity and antimicrobial activity of salvia officinalis L. flowers. Sudan Journal of Medical Sciences Vol. 3, no. 2 (Jun. 2008), pp.127-133.
https://search.emarefa.net/detail/BIM-293206
American Medical Association (AMA)
Abd al-Majid, Muna A. M.& Husayn, Abu Bakr. Cytotoxicity and antimicrobial activity of salvia officinalis L. flowers. Sudan Journal of Medical Sciences. 2008. Vol. 3, no. 2, pp.127-133.
https://search.emarefa.net/detail/BIM-293206
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 129
Record ID
BIM-293206