Cardiac autonomic dysfunction in children and adolescents with type 1 diabetes mellitus
Other Title(s)
اعتلال الأعصاب اللاارادية التي تغذي القلب عند الأطفال و المراهقين المصابين بمرض السكري (النوع الأول)
Joint Authors
al-Amin, Abd al-Aziz
Tuvemo, T.
Rajesh, K.
Source
Sudan Journal of Medical Sciences
Issue
Vol. 2, Issue 2 (30 Jun. 2007), pp.95-101, 7 p.
Publisher
Omdurman Islamic University Faculty of Medicine
Publication Date
2007-06-30
Country of Publication
Sudan
No. of Pages
7
Main Subjects
Topics
Abstract AR
المقدمة و الأهداف : حوالي 13 % من مرضى السكري (النوع الأول) يحدث لهم اعتلال في الجهاز العصبي.
البحث يهدف لدراسة هذه المضاعفات حيث لم يتم وصفها بدقة وسط الأطفال الذين يعانون من ذلك المرض.
المرضى و الطرق : شملت الدراسة عدد 71 مريض يعانون من مرضى السكري (النوع الأول) و كانت أعمارهم أقل من 18 سنة (المتوسط 12 سنة) و كان متوسط مدة إصابتهم بالمرض 3.5 سنة.
تم قياس الجهاز العصبي اللا إرادي بواسطة أربعة اختبارات مختلفة.
النتائج : اتضح أن هؤلاء المرضى يعانون من زيادة خفقان القلب عندما يكون في وضع راحة (بدون بذل جهد) و كذلك اتضح انخفاض ضغط الدم لديهم عندما يكونوا في وضع الوقوف.
الخلاصة : تشير هذه الدراسة إلى أن اعتلال الأعصاب اللا إرادية التي تغذي القلب ليست نادرة وسط الأطفال الذين يعانون من مرض السكري (النوع الأول).
Abstract EN
Introduction : Autonomic neuropathy is less well documented in children with type 1 diabetes mellitus and has received less attention than other diabetic complications.
Sudden death and cardio-respiratory arrest in patients with type 1 and type 2 diabetes mellitus have been cardiac autonomic dysfunction. Aim : The aim of this study was to determine the prevalence of autonomic neuropathy in a cohort of children and adolescents with type I diabetes and to examine the relationship between this complication, and duration of diabetes and degree of glycemic control. Material and Methods : Seventy-six type 1 diabetic children and adolescents below age 18 years of age, and 76 non diabetic school children, matched for age and sex, had their cardiac autonomic nerve function assessed using four autonomic function tests.
Namely the respiratory sinus arrhythmia test ; the Valsalva ratio test ; the heart rate response to standing, and the blood pressure response to standing.
The first three are tests of parasympathetic function, while the last one is a sympathetic function test. Results : The diabetic patients had a median age of 12 years and their median duration of diabetes mellitus was 43 months.
They showed a significantly higher resting heart rate and a significant drop in systolic and diastolic blood pressures upon standing compared to the control group.
The duration of diabetes mellitus showed linear correlation to the symptoms of autonomic dysfunction. Conclusion : We conclude that cardiac autonomic neuropathy is not duration of illness where glycemic control is less than optimal.
Such tests may serve as long-term prognostic indicators in diabetic patients.
American Psychological Association (APA)
al-Amin, Abd al-Aziz& Rajesh, K.& Tuvemo, T.. 2007. Cardiac autonomic dysfunction in children and adolescents with type 1 diabetes mellitus. Sudan Journal of Medical Sciences،Vol. 2, no. 2, pp.95-101.
https://search.emarefa.net/detail/BIM-293286
Modern Language Association (MLA)
Rajesh, K.…[et al.]. Cardiac autonomic dysfunction in children and adolescents with type 1 diabetes mellitus. Sudan Journal of Medical Sciences Vol. 2, no. 2 (Jun. 2007), pp.95-101.
https://search.emarefa.net/detail/BIM-293286
American Medical Association (AMA)
al-Amin, Abd al-Aziz& Rajesh, K.& Tuvemo, T.. Cardiac autonomic dysfunction in children and adolescents with type 1 diabetes mellitus. Sudan Journal of Medical Sciences. 2007. Vol. 2, no. 2, pp.95-101.
https://search.emarefa.net/detail/BIM-293286
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 99-100
Record ID
BIM-293286