Sigmoid colon is an unexpected organ at risk in brachytherapy for cervix cancer
Joint Authors
al-Booz, Huda
Boiangiu, Ion
Applepy, Helen
Chris, French
Coomber, Helen
Humphery, Pauline
Cornes, Paul
Source
Journal of the Egyptian National Cancer Institute
Issue
Vol. 18, Issue 2 (30 Jun. 2006), pp.156-160, 5 p.
Publisher
Cairo University National Cancer Institute
Publication Date
2006-06-30
Country of Publication
Egypt
No. of Pages
5
Main Subjects
Topics
Abstract EN
Purpose : To identify organs at risk (OAR) and analyze the dose volume histograms (DVHs) for intracavitary brachytherapy in cancer of the cervix.
Late toxicities are our concern in treatment of cancer cervix especially as it is presenting in younger age population.
Material and Methods : Patients with cancer of the cervix were treated using CT and MRI compatible, high dose rate, (HDR) applicators.
CT images were acquired with the intra-uterine tube and colpostats in place and subsequently imported into Varian Brachyvision planning software.
We identified the gross tumour volume (GTV) and organs at risk (OARs) and analyzed the dose distribu¬tion using dose volume histograms (DVHs).
Doses were calculated according to ICRU 38.
Critical tissue DVHs were analysed following the American Brachytherapy Society rules.
Dose points are recorded as the dose en¬compassed by the greatest contiguous 1 cm3, 2 cm3, and 5 cm3 volumes in the plan.
Results : We found the sigmoid colon to be a relatively immobile structure that repeatedly received doses in excess of 70 % of the intended point A dose.
The only solution in order to bring sigmoid DVHs within 5 % toxicity limits was to reduce the dose to point A.
Planning images and DVHs for the OARs are shown as an example of our work.
Conclusion : The recto-sigmoid colon is identified as an unexpected OAR in a majority of cervix brachytherapy plans.
A new consensus on the DVH limit of this structure will be needed in the era of CT planned brachytherapy, if arbitrary dose reductions to point A are to be the solution to the problem of sigmoid DVHs that exceed conventional tolerance limits.
American Psychological Association (APA)
al-Booz, Huda& Boiangiu, Ion& Applepy, Helen& Chris, French& Coomber, Helen& Humphery, Pauline…[et al.]. 2006. Sigmoid colon is an unexpected organ at risk in brachytherapy for cervix cancer. Journal of the Egyptian National Cancer Institute،Vol. 18, no. 2, pp.156-160.
https://search.emarefa.net/detail/BIM-29380
Modern Language Association (MLA)
al-Booz, Huda…[et al.]. Sigmoid colon is an unexpected organ at risk in brachytherapy for cervix cancer. Journal of the Egyptian National Cancer Institute Vol. 18, no. 2 (Jun. 2006), pp.156-160.
https://search.emarefa.net/detail/BIM-29380
American Medical Association (AMA)
al-Booz, Huda& Boiangiu, Ion& Applepy, Helen& Chris, French& Coomber, Helen& Humphery, Pauline…[et al.]. Sigmoid colon is an unexpected organ at risk in brachytherapy for cervix cancer. Journal of the Egyptian National Cancer Institute. 2006. Vol. 18, no. 2, pp.156-160.
https://search.emarefa.net/detail/BIM-29380
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 160
Record ID
BIM-29380