The association of age and nutritional status with seroconversion to oral poliovirus vaccine (OPV)‎ in Basrah, Iraq

Abstract EN

dl sewepidemiological study, wot caxxied out in Sfastah, southern 3xaq.

fxom Movembex 1997 until the end of dpxil 1998.

Stood samples were collected fxom 3 souxces; Statwih Jilatexnity and Child Stospital, the ptimaxy health cave centext in Ql-Zu&aix and CLbu-QiSthatib, She relevant information's mete obtained fxom mothexs thxough intexview and J ok vaccination caxds.

CLn £nzyme (inked Jmmunosaxbent assay (CJUSCL) wad used fox the, detection of, poliovixus JgQ antibodies.

{Poliovixus antibodies wexe found in 92.85°/,, with almost full sexoconvexsian among, children above.

2 yeaxs of age, while seronegative cadet wexe ptesent among infant's childxen below, the age of two.

yeaxs and those with old vaccination history and not boosted with additional booster dotes.

Malnourished children have relatively lower levels of, antibody titer than well nowdsfted child/ten.

Number of vaccine dotes given to the child have a significant effect on antibody, ptevalence whew high levels of immunity, wexe found in child/ten who received 5 dotes ok mote while seronegative cases were detected among children who had been given 4 dotes ok less, Shere wexe relatively higher seropotitivity among childxen who received an extxa dotes duxing the Motional Jmmutwiation 2)ays (MJ2)) than among those who did not receive extxa dose(s)j5he antibody levels in the blood it paxtially affected by age and the numbex of vaccine dotes given to the child whexe the proportion of samples with low antibody levels decreased at the age and numbex of vaccine dotes incxeases.

Shexe was cleax evidence fox the overtime antibody losses among the unbaotted childxen.