Early outcome of donors in living-donor liver transplantation at King Hussein Medical Center

Abstract EN

Objectives: To evaluate the safety and early outcome of donors who underwent partial hepatectomy for Living donor- related Liver Transplantation at King Hussein Medical Center (Amman- Jordan).

Methods: We retrospectively reviewed 28 living donors who underwent liver resections (21 right lobes, 5 left lobes, 2 left lateral lobes) for living donor liver transplantation at King Hussein Medical Center.

The procedures were performed over a period of four years from June 2004 till August 2008.

Donor characteristics, operative times, blood loss, hospital stay, and complications as graded by Clavien’s classification were recorded.

Donors were followed- up for a mean period of 8.5 ± 1.91 months (range 6-12 monthes).

Simple descriptive statistical methods (frequency, mean and percentage) were used to describe the study variables Results: A total of 54 potential candidates for living-donor liver transplantations were evaluated.

Of these, 28 underwent successful hepatectomy for donation.

Male to female ratio was 21:7.

The mean age was 28.89 ± 1.30(range 19- 49) years.

A total of 26 potential donors (48%) were excluded at different points of the work- up.

The mean operative times were 6.07 ± 1.12 (rang = 4-8 hours).

The mean intraoperative blood loss were 428.5 ±296.9 (range: 50 to 1500ml), (intraoperative blood transfusion was required for one donor).

Conclusion: Donor hepatectomy in living-donor liver transplantation is a safe procedure.

Meticulous and comprehensive selection protocols are a prerequisite for a good outcome.

Key words: Early outcome, Donor hepatectomy, Liver transplantation.