The interleukin-6 and vascular endothelial growth factor in hematopoietic stem cell transplantation
Joint Authors
Dehghani, Mahdi
Darai, Masumeh
Azarpira, Negar
Source
Saudi Journal of Kidney Diseases and Transplantation
Issue
Vol. 23, Issue 3 (30 Jun. 2012), pp.521-525, 5 p.
Publisher
Saudi Center for Organ Transplantation
Publication Date
2012-06-30
Country of Publication
Saudi Arabia
No. of Pages
5
Main Subjects
Topics
Abstract EN
We studied the correlation between changes in the serum levels of vascular endothelial growth factor (VEGF) and interleukin-6 (IL-6) with complications such as acute graft versus host disease (aGVHD), veno-occlusive disease (VOD) or occurrence of infection after hematopoietic stem cell transplantation (HSCT).
Serum VEGF and IL-6 levels were sequentially measured by enzyme-linked immunosorbant assay (ELISA) in 35 patients who had undergone HSCT.
Serum levels of IL-6 in patients with aGVHD were increased in comparison with patients without aGVHD, but the difference was not statistically significant.
Serum levels of VEGF were only increased in patients with aGVHD during the early days after transplantation.
No significantly altered levels of IL-6 and VEGF were observed in patients with VOD or sepsis.
These results demonstrate that rising levels of VEGF and IL-6 may be good and specific biomarkers for transplant aGVHD.
American Psychological Association (APA)
Azarpira, Negar& Dehghani, Mahdi& Darai, Masumeh. 2012. The interleukin-6 and vascular endothelial growth factor in hematopoietic stem cell transplantation. Saudi Journal of Kidney Diseases and Transplantation،Vol. 23, no. 3, pp.521-525.
https://search.emarefa.net/detail/BIM-297463
Modern Language Association (MLA)
Azarpira, Negar…[et al.]. The interleukin-6 and vascular endothelial growth factor in hematopoietic stem cell transplantation. Saudi Journal of Kidney Diseases and Transplantation Vol. 23, no. 3 (Jun. 2012), pp.521-525.
https://search.emarefa.net/detail/BIM-297463
American Medical Association (AMA)
Azarpira, Negar& Dehghani, Mahdi& Darai, Masumeh. The interleukin-6 and vascular endothelial growth factor in hematopoietic stem cell transplantation. Saudi Journal of Kidney Diseases and Transplantation. 2012. Vol. 23, no. 3, pp.521-525.
https://search.emarefa.net/detail/BIM-297463
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 524-525
Record ID
BIM-297463