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Mean density of hemoglobin, a better discriminator of iron deficiency anemia from thalassemia minor
Joint Authors
Rajabiani, A.
Ghaffuri, M.
Hishmati, P.
Source
Iranian Red Crescent Medical Journal
Issue
Vol. 8, Issue 2 (30 Sep. 2005), pp.47-50, 4 p.
Publisher
Publication Date
2005-09-30
Country of Publication
United Arab Emirates
No. of Pages
4
Main Subjects
Topics
Abstract EN
Background : Distinguishing 1wocommon hypochromic microcytic anemias (i.e.
iron deflciencyanemia and thalassemia) needs expensive laboratory tests not readily available everywhere.
For better discrimination of minor thalassemia from Iron deficiency anemia some formulas are available, of them four formulas of England, Mentzer, Shine and MDHL are compared here and superiority of MDHL proved.
Methods : The four indices were calculated for 10Bproved thalassemia minor patients and 199 Iron deficients (total 307 cases).
The best cut-off point for each index was selected by received operator characteristics analysis reaching the highest sensitivity possible to separate thalassemics form.
Iron deficients.
Sensitivity, speciflclty and efficacy of indices were compared.
Results : Mentzer's index (sensitivity : 93.5, specificity: 82.0, efficacy : 86.64) and MDHL (sensitivity : 95.4, specificity : 80.9, efficacy : 85.99) had better results.
Interpretation: It seems that these indices can be used to screen microcytic ; anemlc pateitns, reserving haemoglobin electrophoresis, genetic studies, serum iron and ferritin measurement for selected patients, lowering public health costs.
American Psychological Association (APA)
Rajabiani, A.& Hishmati, P.& Ghaffuri, M.. 2005. Mean density of hemoglobin, a better discriminator of iron deficiency anemia from thalassemia minor. Iranian Red Crescent Medical Journal،Vol. 8, no. 2, pp.47-50.
https://search.emarefa.net/detail/BIM-29760
Modern Language Association (MLA)
Rajabiani, A.…[et al.]. Mean density of hemoglobin, a better discriminator of iron deficiency anemia from thalassemia minor. Iranian Red Crescent Medical Journal Vol. 8, no. 2 (Sep. 2005), pp.47-50.
https://search.emarefa.net/detail/BIM-29760
American Medical Association (AMA)
Rajabiani, A.& Hishmati, P.& Ghaffuri, M.. Mean density of hemoglobin, a better discriminator of iron deficiency anemia from thalassemia minor. Iranian Red Crescent Medical Journal. 2005. Vol. 8, no. 2, pp.47-50.
https://search.emarefa.net/detail/BIM-29760
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 50
Record ID
BIM-29760