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Glutathione as potential target for cancer therapy ; more or less is good ? (mini-review)
Author
Source
Jordan Journal of Biological Sciences
Issue
Vol. 4, Issue 3 (30 Sep. 2011), pp.119-124, 6 p.
Publisher
The Hashemite University Deanship of Academic Research and Graduate
Publication Date
2011-09-30
Country of Publication
Jordan
No. of Pages
6
Main Subjects
Topics
Abstract EN
Glutathione (GSH) plays important roles in antioxidant defense, nutrient metabolism, and regulation of cellular processes, including cell differentiation, proliferation and apoptosis.
Glutathione deficiency contributes to oxidative stress, which plays a key role in aging and pathogenesis of many diseases, one of which is cancer.
The GSH content of cancer cells is associated with multidrug and radiation resistance.
Just as low intracellular GSH levels decrease cellular antioxidant capacity, elevated GSH levels generally increase antioxidant capacity and resistance to oxidative stress, and this phenomenon is observed in may cancer cells as compared to normal ones.
The present review will address the following questions: what is cancerglutathione relation? Can glutathione play a role in treating or preventing cancer?
American Psychological Association (APA)
Abd Allah, Mahir Y.. 2011. Glutathione as potential target for cancer therapy ; more or less is good ? (mini-review). Jordan Journal of Biological Sciences،Vol. 4, no. 3, pp.119-124.
https://search.emarefa.net/detail/BIM-297948
Modern Language Association (MLA)
Abd Allah, Mahir Y.. Glutathione as potential target for cancer therapy ; more or less is good ? (mini-review). Jordan Journal of Biological Sciences Vol. 4, no. 3 (Sep. 2011), pp.119-124.
https://search.emarefa.net/detail/BIM-297948
American Medical Association (AMA)
Abd Allah, Mahir Y.. Glutathione as potential target for cancer therapy ; more or less is good ? (mini-review). Jordan Journal of Biological Sciences. 2011. Vol. 4, no. 3, pp.119-124.
https://search.emarefa.net/detail/BIM-297948
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 123-124
Record ID
BIM-297948