Profile of antibiotic sensitivity and resistance of some pathogenic bacteria isolated from clinical specimens in Sudan

Abstract EN

In this study the activity of gentamicin, ciprofloxacin, ceftazidinime impenem, amikacin, tetracycline, penicillin, nalidixic acid and nitrofurantoin was evaluated.

A total of 380 clinical specimens were collected from different hospitals in Khartoum state.

Different types of bacteria were isolated.

These include Staphylococcus aureus (n=37), Escherichia coli (n=70), Klebsiella pneumoniae (n=15), Proteus spp.

(n=57) and Pseudomonas aeruginosa (n=67).The study revealed that the profile of antibiotics sensitivity and resistance were as follows: Gentamicin 90.8 and 9.2%, ciprofloxacin 72.1 and 27.9%, ceftazidinime 100.0 and 0.0%, impenem 100.0 and 0.0%, amikacin 94.0 and 6.0%, tetracycline 47.7 and 52.3%, nalidixic acid 65.9 and 34.1% and nitrofurantoin 86.3 and 13.7%, penicillin 16.7 and 83.3% and erythromycin 75.9 and 24.1% respectively.

The study concluded that ceftazidinime and impenem were the most effective antibiotics against Pseudomonas aeruginosa isolated from wounds.

KEYWORDS: Antibiotic sensitivity and resistance, Pathogenic bacteria.