Haematological changes in malaria infected blood stored in blood bank refrigerator (1-6°C)‎

Abstract EN

The intension of this study is to detect the haematological changes in malaria parasite infected stored blood as compared to non-infected stored blood.

A total of 4484 blood donors, recruited for this study, are screened microscopically for malaria parasites using Giemsa’ stain technique.

Only 30 blood samples (200ml each), were found to be positive, and satisfied the inclusion criteria of the study.

Also 30 malaria negative blood samples are included in the study for such comparison.

Blood specimens are then tested by hematological and biochemical techniques on the same day then after 24 and 48hours storage in blood bank refrigerator.

Platelets counts and serum potassium level in malaria infected blood are significantly different from that in non-infected blood on the day of collection, after 24hours and after 48hours, while the PCV is significantly different after 24 and 48hours only.

Activated partial thromboplastin time and serum sodium levels show significant statistical difference after 48hours storage only.

Prothrombin time, Osmotic fragility, and total leucocyte counts are similar on both samples on the day of collection, after 24hours and 48hours.

Considering the dilution of the donated blood by the anticoagulant solution, haematological values in malaria-infected blood are within the normal range in spite of the significant statistical difference from the non-infected blood.

It is recommended, that, to process donated blood in vitro: clear malaria parasites and then use the cleared blood in transfusion practice.