Alpha blocker therapy for the treatment of idiopathic oligozoospermia

Abstract EN

Objectives : To evaluate the efficacy of an alpha-blocker (prazosin) for the treatment of idiopathic oligozoospermia.

Methods : The study group included 18 infertile men aged 26 to 45 years (with mean age of 35 years) with sperm densities between 5 to 20 × 106 supermall, normal serum gonadotropins, testosterone, and prolactin level.

Patients were prescribed prazosin - 2mgld for six months.

Semen samples were collected before and three months and six months after therapy.

Semen parameters were evaluated before and after the treatment.

Results : The Pregnancy Rate (PR) was 27.7%.

There were a significant increase in sperm concentration and total-motile sperm count.

Conclusion : It appears that an alpha-blocker (prazosin); is a useful drug in the treatment of idiopathic oligospermic males.