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The effects of fumitory parviflora extract on gastric acid and pepsin secretion in rat
Joint Authors
Nabavizadeh, F.
Iran, Manesh E.
Sohbati, S.
Source
Iranian Red Crescent Medical Journal
Issue
Vol. 7, Issue 3 (31 Jan. 2005), pp.59-62, 4 p.
Publisher
Publication Date
2005-01-31
Country of Publication
United Arab Emirates
No. of Pages
4
Main Subjects
Abstract EN
Background : Fumitory-parviflora is a plant from papaveracea family that is used for treatment of some GI tract diseases.
Sofar there hasn't been a study performed on the effects of extract of fumitory-parviflora on gastric acid and pepsin secretion.
This study is designed to define the effect of the extract of fumitory-parviflora on basal and pentagastrin induced gastric acid and pepsin secretion in rat.
Methods : Both of the groups were anesthetized with sodium thiopental.
The test group received 600 mg / kg, IP fumitory-parviflora extract.
After tracheostomy and laparotomy gastric effluents were collected by wash out technique in 15 minute intervals and total titrable acid was measured by acid testator.
The pepsin content was measured by Anson method.
Pentagastrin (25µg / kg, IP) was used to stimulate the secretion of acid and pepsin.
Results : The results of this experiment showed no significant differences between basal acid and pepsin secretion in group that received extracts of fumitory-parviflora in comparison to the control group.
According to the results, there was a significant difference between amount of basal and stimulated acid secretion in the control group but not in the test group.
There was significant increase of pepsin secretion after stimulation in comparison to basal state in both groups.
Also this difference in the control group is significantly more than the test group.
Conclusion : Fumitory-parviflora prohibits the stimulatory effect of pentagastrin on acid and pepsin secretion
American Psychological Association (APA)
Nabavizadeh, F.& Iran, Manesh E.& Sohbati, S.. 2005. The effects of fumitory parviflora extract on gastric acid and pepsin secretion in rat. Iranian Red Crescent Medical Journal،Vol. 7, no. 3, pp.59-62.
https://search.emarefa.net/detail/BIM-30004
Modern Language Association (MLA)
Nabavizadeh, F.…[et al.]. The effects of fumitory parviflora extract on gastric acid and pepsin secretion in rat. Iranian Red Crescent Medical Journal Vol. 7, no. 3 (Jan. 2005), pp.59-62.
https://search.emarefa.net/detail/BIM-30004
American Medical Association (AMA)
Nabavizadeh, F.& Iran, Manesh E.& Sohbati, S.. The effects of fumitory parviflora extract on gastric acid and pepsin secretion in rat. Iranian Red Crescent Medical Journal. 2005. Vol. 7, no. 3, pp.59-62.
https://search.emarefa.net/detail/BIM-30004
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references : p. 62
Record ID
BIM-30004