Intraperitoneal lidocaine for postoperative pain relief after laparoscopic ovarian drilling

Abstract EN

Objective: to evaluate the efficacy and safety of intraperitoneal installation of lidocaine as regards postoperative analgesia after laparoscopic ovarian drilling for polycystic ovarian syndrome (PCOs).

Study design: A prospective, randomized placebo controlled study.

Setting department of Obstetrics and Gynecology, maternal health center, Assuit University, Assuit, Egypt. Patients and methods: This study v>as done upon fifty women undergoing operative laparoscopic ovarian drilling for polycystic ovarian syndrome (PCOs) under general anaesthesia, all patients were subjected to skin infiltration of 2.5 ml of lidocaine 2% at the site of Verres needle and trocar insertion.

Patients were allocated randomly to one of two groups; group A (lidocaine group) 25 patients received 150 mg intraperitoneal lidocaine hydrochloride in the Douglas pouch, 50mg before Co2 inflation and lOOmg left in the peritoneal cavity, and the group B (control group) 25 patients received only saline (0.9 % NaCl) instead of lidocaine.

Shoulder and pelvic pain were evaluated using visual analogue score, postoperative analgesic requirements (the need for intramuscular non-steroidal antiinflammatory drugs, ketorolac 30), and time to return to normal daily activities were evaluated in the ambulatory unit and after discharge during the first 48 postoperative hours, The collected data were analyzed using SPSS (statistical package for social science) program and Chi square test (the probability of error P). Results: Pain score, analgesic requirements and time to return to normal daily activities were significantly reduced in patients who received intraperitoneal lidocaine (P<0.05). Conclusion: Intraperitoneal installation of 150 mg lidocaine is simple to use, resulting in effective long lasting analgesia and improves the postoperative course.