Assessment of thyroid function in pregnant women from Rimal Health Center, Gaza City

Other Title(s)

تقيم وظائف الغدة الدرقية لدى النساء الحوامل من مركز الرمال الصحي في مدينة غزه

Dissertant

Radi, Raghdah Abd al-Latif Abd al-Latif

Thesis advisor

Yasin, Majid M.

Comitee Members

Zabut, Bakir Mahmud
Shubayr, Muhammad Id

University

Islamic University

Faculty

Faculty of Science

Department

Department of Biological Science

University Country

Palestine (Gaza Strip)

Degree

Master

Degree Date

2010

English Abstract

Background : pregnancy is associated with significant but reversible changes inn thyroid function tests results, which are as a result of a normal physiologic state.

Pregnancy influences thyroid function and may bring to light mild and latent disorders.

This study focused on thyroid hormones as the human fetal thyroid does not secrete thyroid hormones until approximately 12 weeks of gestation, the fetus is dependent until that time on a supply from the maternal circulation.

Thyroid dysfunction has been related to obstetrical complications such as premature delivery, gestational hypertension, preeclampsia, and placental abruption.

Objective : to assess the maternal thyroid function in the first trimester of pregnant women from Rimal health center-Gaza city Materials and methods.

A cross sectional study was designed with 90 normal pregnant women who were randomly selected from the first trimesters attending Rimal Health Center and 80 randomly selected non-pregnant healthy female controls.

Age range in both groups was 18-40 years.

Thyroid function tests were carried out by measuring serum levels of thyroid stimulating hormone (TSH), free thyroxin (FT4), and free triiodothyronine (FT3).

They were measured using Micro particles Enzyme Immunoassay (MEIA).

SPSS was used to analyse obtained data.

Results : the results showed that there was a significant increased between the non-pregnant women group and pregnant women for FT4 and FT3 where the p-value is 0.04 and 0.030 respectively.

The mean TSH levels of pregnant women was lower than the mean level of non-pregnant but did not show significant difference in first trimester compared with non-pregnant women.

Also there was a significant statistical difference between the groups of different age for FT4 and FT3 where the p- value was 0.034 and 0.038 among the non-pregnant women group.

On the other hand, there was no statistically significant relationship between thyroid function in pregnancy and family history of thyroid problems, genetic disease, and hypertension among women in the study sample.

Main Subjects

Public Health
Medicine

Topics

No. of Pages

77

Table of Contents

Abstract.

Table of contents.

Chapter one : Introduction.

Chapter two : Literature review.

Chapter three : Materials and methods.

Chapter four : Results.

Chapter five : Discussion.

Chapter six : Conclusion and recommendations.

References.

American Psychological Association (APA)

Radi, Raghdah Abd al-Latif Abd al-Latif. (2010). Assessment of thyroid function in pregnant women from Rimal Health Center, Gaza City. (Master's theses Theses and Dissertations Master). Islamic University, Palestine (Gaza Strip)
https://search.emarefa.net/detail/BIM-303494

Modern Language Association (MLA)

Radi, Raghdah Abd al-Latif Abd al-Latif. Assessment of thyroid function in pregnant women from Rimal Health Center, Gaza City. (Master's theses Theses and Dissertations Master). Islamic University. (2010).
https://search.emarefa.net/detail/BIM-303494

American Medical Association (AMA)

Radi, Raghdah Abd al-Latif Abd al-Latif. (2010). Assessment of thyroid function in pregnant women from Rimal Health Center, Gaza City. (Master's theses Theses and Dissertations Master). Islamic University, Palestine (Gaza Strip)
https://search.emarefa.net/detail/BIM-303494

Language

English

Data Type

Arab Theses

Record ID

BIM-303494