Evaluation the levels of serum hormones (progesterone, estradiol, and hCG)‎ in preeclamptic Iraqi pregnancies

Abstract EN

This study aimed to evaluate serum levels of steroid hormones and human chorionic gonadotropin (HCG) hormone in preeclampsia Iraqi pregnancies compared to those of healthy pregnancies.

This study enrolled 120 pregnant women, divided into four groups ; 1.

30 healthy pregnant women.

2.

27 pregnant women with mild preeclampsia.

3.

53 pregnant women with severe preeclampsia.

4.

90 pregnant women with preeclampsia.

Preeclampsia women and their severe cases but not mild cases had significantly (P < 0.01) increased levels of serum HCG as compared with healthy pregnancies.

By contrast, sera levels of estradiol were significantly (P < 0.01) decreased in total preeclampsia groups and their severe cases but not in mild group as compared to healthy pregnant women (controls), while there were no significant differences in the levels of serum progesterone in all preeclampsia groups as compared with controls.

This study that concludes Preeclampsia is associated with increased levels of HCG hormone and decreased levels of estradiol hormone and this support the suggestion of the role of hormones in preeclampsia.