Synthesis and characterization co-polymer of aspargine and cephalexin

Abstract EN

In this work a new peptide-base polymer were synthesized by polycondensation of cephalexinyl chloride and asparginyl chloride.

This synthesized biopolymer is especially interesting because its primary structure allows the specific cleavage through amide group, can also be used for site specific release of drug as we expected. The physical properties of [C3] were measured., FT-IR, 1H-NMR and UV.

Spectroscopy used to characterized the polymer [C3].

S % was calculated in water, and controlled release was studied in different pH values at 37C.