The effect of ginger (zingibar officinale)‎ aqueous extract on some biochemical parameters and kidney function in male mice

Abstract EN

Ginger has become a subject of interest because of its beneficial effect on human health.

The purpose of the present study was to investigate the effect of daily intraperitoneal injection of ginger extract for four weeks on some biochemical parameters (serum cholesterol, RBS, HDL, LDL) and kidney functions (urea, uric acid, creatinine).

24 Mice were divided into three groups, normal control group and two treated groups, each group contain eight mice.

They were injection intraperitoneal with 0.1ml distill water to control group while two treated groups received the same dose of ginger extract (1mg,2 mg / mice) respectively for four weeks Bio chemical's parameters (blood glucose, serum cholesterol, LDL) showed significant decrease (p < 0.01), while (HDL) appeared significant increase when compared with control group.

On the other hand study of kidney function showed significant decrease in (urea, uric acid, and creatinine) when compared it with control group.