Correlation of maternal C-reactive protein and s. fibrinogen with the severity of pre-eclampsia

Abstract EN

Objective : the aim of this study was to determine the level of plasma fibrinogen and Creactive protein in pre-eclampsia and their associations with severity of the disease. Study design : C-reactive protein and plasma fibrinogen levels were investigated in 26 cases of normal pregnant women,26 cases with mild pre-eclampsia ,26 cases with sever pre-eclampsia in the third trimester of pregnancy.

Mean atrial pressure (MAP) was used as indicator of the severity of the disease .Analysis of variance with kruskal-wallis test used when the three groups were compared. Result : C-reactive protein and plasma fibrinogen levels in mild and sever pre-eclampsia patients were markedly higher than that of normal third trimester pregnant women. Conclusion : we found higher levels of plasma fibrinogen and C-reactive protein and presence of a good correlation between C-RP and MAP in pre-eclampsia.