Some reactions of symmetrical aromatic aldazines with dimethyl acetylenedicarboxylate

Dissertant

al-Halasah, Rasha Jamal

Thesis advisor

al-Allali, Abd Allah

Comitee Members

Jaradat, Qasim Muhammad Khayr
Tashtush, Hasan

University

Mutah University

Faculty

Faculty of Science

Department

Department of Chemistry

University Country

Jordan

Degree

Master

Degree Date

2002

English Abstract

Some aromatic symmetrical aldazines, which are actually heterodienes, reacted here not as 1, 3-heterodienes in [4 + 2]-cycloaddition but as 1, 3-dipolar compounds.

Their reactions with two moles of dimethyl acetylenedicarboxylate led to [3 + 2]-cycloaddition reactions, which known as criss-cross cycloaddition. These reactions gave two different azine porducts, namly, bicyclic azines and N-allyl pyrazoles depending on the nature of the aldehyde used.

The N-allyl pyrazoles were found to possess high biological activity, whereas the bicyclic azine possesses low to medium activity.

Characterization of the products was achieved by 'H-NMR, 13C-NMR, IR spectroscopy and elemental analysis.

Main Subjects

Chemistry

Topics

• Chemical processes
• Organic compounds
• Aromatic compounds
• Chemical reactions

No. of Pages

81

Table of Contents

• APA
• MLA
• AMA

Language

English

Data Type

Arab Theses

Record ID

BIM-309616