Pregnancy after mechanical mitral valve replacement
Joint Authors
Kashfi, Fahimeh
Sami, Nilufar
Khamoushi, Amir Jamshid
Husayni, Saeid
Ghavidel, Alireza Alizadeh
Taheripanah, Robabeh
Source
Iranian Red Crescent Medical Journal
Issue
Vol. 14, Issue 12 (31 Dec. 2012)12 p.
Publisher
Publication Date
2012-12-31
Country of Publication
United Arab Emirates
No. of Pages
12
Main Subjects
Topics
Abstract EN
Background : Pregnant patients with mechanical heart valves require anticoagulation.
The risk of bleeding and embryopathy associated with oral anticoagulation must be weighed against the risk of valve thrombosis. Objectives : This study attempted to find the fatal outcome between warfarin and heparin regiments throughout pregnancy. Patients and Methods : In this prospective study undertaken between 1999 and 2009, 53 pregnancies (47 women with mechanical mitral valve ; 29.8 ± 4.8 years old) were studied.
Patients were divided in two groups, group I (n = 43) took warfarin throughout the pregnancy while, group II (n = 10) received heparin in the first trimester and after took warfarin that until 36 weeks. Results : Thirty-two pregnancies (60.4 %) resulted in live births while 18(34 %) abortions, 2 (3.8 %) still births and one (1.9 %) maternal death occurred.
In group I, there were 26 live births (60.5 %), one still birth (2.3 %) and 15 (34.9 %) abortions.
In group II there were 6 (60 %) live births, one (10 %) still birth and 3(30%) abortions.
There were no significant differences between two groups in fetal outcome.
Thirty –Nine (90.7 %) pregnancies in group I and in groups II 50 % (P = 0.001) occurred without complication .There were no congenital malformations in two groups. Conclusions : Fetal outcome was almost same between warfarin and heparin regimens.
In maternal outcome, warfarin regimen is safer than heparin.
American Psychological Association (APA)
Kashfi, Fahimeh& Sami, Nilufar& Khamoushi, Amir Jamshid& Husayni, Saeid& Ghavidel, Alireza Alizadeh& Taheripanah, Robabeh. 2012. Pregnancy after mechanical mitral valve replacement. Iranian Red Crescent Medical Journal،Vol. 14, no. 12.
https://search.emarefa.net/detail/BIM-310927
Modern Language Association (MLA)
Kashfi, Fahimeh…[et al.]. Pregnancy after mechanical mitral valve replacement. Iranian Red Crescent Medical Journal Vol. 14, no. 12 (Dec. 2012).
https://search.emarefa.net/detail/BIM-310927
American Medical Association (AMA)
Kashfi, Fahimeh& Sami, Nilufar& Khamoushi, Amir Jamshid& Husayni, Saeid& Ghavidel, Alireza Alizadeh& Taheripanah, Robabeh. Pregnancy after mechanical mitral valve replacement. Iranian Red Crescent Medical Journal. 2012. Vol. 14, no. 12.
https://search.emarefa.net/detail/BIM-310927
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references.
Record ID
BIM-310927