![](/images/graphics-bg.png)
Evaluation of serum cyfra21 in patients with pleural effusion
Joint Authors
Azimi, Q.
Rezadoost, B.
Nadoushan, M. Jalali
Davati, A.
Source
Iranian Red Crescent Medical Journal
Issue
Vol. 14, Issue 10 (31 Oct. 2012)5 p.
Publisher
Publication Date
2012-10-31
Country of Publication
United Arab Emirates
No. of Pages
5
Main Subjects
Topics
Abstract EN
Background : The aim of this study is to determine the level of serum cytokeratin19 fragment (cyfra21-1) in patients with benign or malignant pleural effusion and evaluation the sensitivity and specificity of this tumor marker. Method and Material : We prospectively evaluated 98 patients (39 malignant, 54 benign and the results were inconclusive in 5) with pleural effusion.
The diagnosis of malignant pleural effusion was defined by cytological or histological results.
We used serum cyfra21-1 criteria from literature of Roch company.
Level of the marker was determined using electrochemiluminescence. Results : There was statistically significant difference between mean of serum cyfra21-1 levels of benign (3.9 ± 7.6) and malignant(19.5 ± 30) pleural effusion (p=0.01).
In addition the sensitivity, specificity, positive predictive value and negative predictive value of serum cyfra21-1 at the cutoff point of 3.3 ng / ml, was 84 % , 61 %, 61 % and 84 % respectively. Conclusion : Serum cyfra21-1 is useful as a measure in differentiating malignant from benign pleural effusion.
American Psychological Association (APA)
Azimi, Q.& Rezadoost, B.& Nadoushan, M. Jalali& Davati, A.. 2012. Evaluation of serum cyfra21 in patients with pleural effusion. Iranian Red Crescent Medical Journal،Vol. 14, no. 10.
https://search.emarefa.net/detail/BIM-310990
Modern Language Association (MLA)
Azimi, Q.…[et al.]. Evaluation of serum cyfra21 in patients with pleural effusion. Iranian Red Crescent Medical Journal Vol. 14, no. 10 (Oct. 2012).
https://search.emarefa.net/detail/BIM-310990
American Medical Association (AMA)
Azimi, Q.& Rezadoost, B.& Nadoushan, M. Jalali& Davati, A.. Evaluation of serum cyfra21 in patients with pleural effusion. Iranian Red Crescent Medical Journal. 2012. Vol. 14, no. 10.
https://search.emarefa.net/detail/BIM-310990
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references.
Record ID
BIM-310990