Effects of acetaminophen consumption in asthmatic children
Joint Authors
Oshnouei, S.
Salarilak, Sh.
Khalkhali, A.
Karamyar, M.
Rad, M. H. Rahimi
Delpisheh, Ali
Source
Iranian Red Crescent Medical Journal
Issue
Vol. 14, Issue 10 (31 Oct. 2012)6 p.
Publisher
Publication Date
2012-10-31
Country of Publication
United Arab Emirates
No. of Pages
6
Main Subjects
Topics
Abstract EN
Background : Acetaminophen exposure might be associated with increasing risk of asthma prevalence and other atopic disorders over recent decades.
The present study aimed to investigate the association between acetaminophen exposure and the risk of developing childhood asthma. Methods : A case - control study was undertaken between March and September 2010 in Urmia district north west of Iran.
Subjects were children aged between 2 - 8 years old.
Cases were asthmatic children diagnosed based on GINA criteria (n = 207) and controls were children without asthma symptoms (n=414) using 1 : 2 sampling method.
Cases and controls were matched for age and gender.
Clinical data including Acetaminophen exposure was collected by a questionnaire which completed by interviewing with parents / guardians. Results : Using Acetaminophen during the first year of life had no any effect on the risk of asthma (p=0.19), but amongst 2-8 years old children, this association was observed(p < 0.001).
There was also a doseresponse association between Acetaminophen consumption and risk of asthma (OR : 3.8 ; 95 % CI ; 2.15 6.59 for once per 2 to 3 month and OR : 4.2 ; 2.50 - 7.3 for at least one per month). Conclusions : Using Acetaminophen increases risk of asthma among 2 - 8 years old children.
However stronger evidences are required to design evidence-based guidelines to reduce acetaminophen consumption following post - vaccination and other febrile disorders.
American Psychological Association (APA)
Oshnouei, S.& Salarilak, Sh.& Khalkhali, A.& Karamyar, M.& Rad, M. H. Rahimi& Delpisheh, Ali. 2012. Effects of acetaminophen consumption in asthmatic children. Iranian Red Crescent Medical Journal،Vol. 14, no. 10.
https://search.emarefa.net/detail/BIM-311002
Modern Language Association (MLA)
Oshnouei, S.…[et al.]. Effects of acetaminophen consumption in asthmatic children. Iranian Red Crescent Medical Journal Vol. 14, no. 10 (Oct. 2012).
https://search.emarefa.net/detail/BIM-311002
American Medical Association (AMA)
Oshnouei, S.& Salarilak, Sh.& Khalkhali, A.& Karamyar, M.& Rad, M. H. Rahimi& Delpisheh, Ali. Effects of acetaminophen consumption in asthmatic children. Iranian Red Crescent Medical Journal. 2012. Vol. 14, no. 10.
https://search.emarefa.net/detail/BIM-311002
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references.
Record ID
BIM-311002