Randomized control trial : comparison of triple therapy plus probiotic yogurt vs. standard triple therapy on helicobacter pylori eradication
Joint Authors
Source
Iranian Red Crescent Medical Journal
Issue
Vol. 14, Issue 10 (31 Oct. 2012)10 p.
Publisher
Publication Date
2012-10-31
Country of Publication
United Arab Emirates
No. of Pages
10
Main Subjects
Abstract EN
Background : Treatment of Helicobacter pylori (H.
pylori) as a major cause of gastric diseases is of utmost concern.
We aimed to assess efficacy of triple therapy (amoxicillin, clarithromycin and pantoprazole) plus probiotic yogurt (PY) on eradication of H.pylori. Methods : Total 102 H.
pylori positive patients were divided to 3 groups equally and randomly.
For treatment of each group Amoxicillin, clarithromycin and pantoprazole were used.
Group A had additional PY, Group B ordinary low fat yogurt and Group C just had triple therapy in their regimen as well.
These groups were compared regarding treatment success. Results : Total number of 88 patients finished the treatment course.
The most common experienced side effects were dysgeusia in groups A and B (25.8 % and 32.3 %, respectively), and dysgeusia with diarrhea and abdominal pain (30.8 %) in group C.
Eradication rate was, respectively, 61.3%, 64.5% and 71.3 % in group A, B and C of which difference was not statistically significant (P > 0.05).
However, the difference between 3 groups in regard to education level was statistically significant (P = 0.005). Conclusion : PY enriched triple therapy has decreased side effects of antibiotics consumption ; however, this has no impact on eradication of Hpylori.
PY and triple therapy can be used concomitantly to increase the patient tolerance.
American Psychological Association (APA)
Mirzaee, V.& Rezahoseini, O.. 2012. Randomized control trial : comparison of triple therapy plus probiotic yogurt vs. standard triple therapy on helicobacter pylori eradication. Iranian Red Crescent Medical Journal،Vol. 14, no. 10.
https://search.emarefa.net/detail/BIM-311006
Modern Language Association (MLA)
Mirzaee, V.& Rezahoseini, O.. Randomized control trial : comparison of triple therapy plus probiotic yogurt vs. standard triple therapy on helicobacter pylori eradication. Iranian Red Crescent Medical Journal Vol. 14, no. 10 (Oct. 2012).
https://search.emarefa.net/detail/BIM-311006
American Medical Association (AMA)
Mirzaee, V.& Rezahoseini, O.. Randomized control trial : comparison of triple therapy plus probiotic yogurt vs. standard triple therapy on helicobacter pylori eradication. Iranian Red Crescent Medical Journal. 2012. Vol. 14, no. 10.
https://search.emarefa.net/detail/BIM-311006
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references.
Record ID
BIM-311006