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Decreased serum level of soluble-leptin-receptor in patients with systemic lupus erythematosus
Joint Authors
Ebadi, P.
Bagheri, K.
Nuaymi, S.
Source
Iranian Red Crescent Medical Journal
Issue
Vol. 14, Issue 9 (30 Sep. 2012)7 p.
Publisher
Publication Date
2012-09-30
Country of Publication
United Arab Emirates
No. of Pages
7
Main Subjects
Topics
Abstract EN
Background : There is some evidence suggesting that leptin and its negative regulator, soluble-leptinreceptor (SLR) may be able to influence inflammatory and autoimmune processes. Methods : In this study, several variables including socio-demographics, health-related habits, depression score, serum molecules and blood parameters besides the SLR level were evaluated in patients with SLE (SLE-patients) and healthy controls. Results : The patients had significantly lower SLR level and higher depression score than the controls and both of these variables have a significant association with the occurrence of disease in logistic regression model.
Moreover, the results of Pearson correlation analysis showed that patients’ SLR level was negatively correlated with their weights and BDI scores. Conclusion : For the first time, this study indicated a lower level of SLR in SLE-patients and suggested that lower concentrations of SLR in these patients may be implicated in the pathogenesis of SLE.
American Psychological Association (APA)
Bagheri, K.& Ebadi, P.& Nuaymi, S.. 2012. Decreased serum level of soluble-leptin-receptor in patients with systemic lupus erythematosus. Iranian Red Crescent Medical Journal،Vol. 14, no. 9.
https://search.emarefa.net/detail/BIM-311016
Modern Language Association (MLA)
Bagheri, K.…[et al.]. Decreased serum level of soluble-leptin-receptor in patients with systemic lupus erythematosus. Iranian Red Crescent Medical Journal Vol. 14, no. 9 (Sep. 2012).
https://search.emarefa.net/detail/BIM-311016
American Medical Association (AMA)
Bagheri, K.& Ebadi, P.& Nuaymi, S.. Decreased serum level of soluble-leptin-receptor in patients with systemic lupus erythematosus. Iranian Red Crescent Medical Journal. 2012. Vol. 14, no. 9.
https://search.emarefa.net/detail/BIM-311016
Data Type
Journal Articles
Language
English
Notes
Includes bibliographical references.
Record ID
BIM-311016